Article
Recessive mutations in CAKUT and VACTERL association.
Kidney international - 1 Jun 2014
Westland Rik, Sanna-Cherchi Simone
Abstract excerpt
Understanding the complex genetic makeup underlying congenital anomalies of the kidney and urinary tract (CAKUT) is of primary importance to improve diagnosis, stratify risk for later-onset complications, and develop therapeutic strategies. Saisawat et al. used homozygosity mapping coupled with next-generation sequencing to identify recessive mutations in TRAP1 in families with isolated CAKUT and with VACTERL...
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