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Article

EP300 knockdown reduces cancer stem cell phenotype, tumor growth and metastasis in triple negative breast cancer.

BMC cancer - 10 Nov 2020

Ring Alexander, Kaur Pushpinder, Lang Julie E

Abstract excerpt

BACKGROUND: Triple negative breast cancer (TNBC) is an aggressive breast cancer subtype with basal features, lacking the expression of receptors targeted successfully in other breast cancer subtypes. Treatment response to adjuvant and neoadjuvant chemotherapy is often short-lived and metastatic spread occurs at higher rates than other subtypes within the first five years after diagnosis. TNBCs exhibit stem cell...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 33167919
DOI: 10.1186/s12885-020-07573-y
PMCID: PMC7653866

Genes

EP300
ABCG2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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EP300 knockdown reduces cancer stem cell phenotype, tumor growth and metastasis in triple negative breast cancer.PMID 33167919Read ↗

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