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Article

Placenta-derived macaque trophoblast stem cells: differentiation to syncytiotrophoblasts and extravillous trophoblasts reveals phenotypic reprogramming.

Scientific reports - 5 Nov 2020

Schmidt Jenna Kropp, Keding Logan T, Block Lindsey N, Wiepz Gregory J, Koenig Michelle R, Meyer Michael G, Dusek Brittany M, Kroner Kamryn M, Bertogliat Mario J, Kallio Avery R, Mean Katherine D, Golos Thaddeus G

Abstract excerpt

Nonhuman primates are excellent models for studying human placentation as experimental manipulations in vitro can be translated to in vivo pregnancy. Our objective was to develop macaque trophoblast stem cells (TSCs) as an in vitro platform for future assessment of primate trophoblast development and function. Macaque TSC lines were generated by isolating first and second trimester placental villous...

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Identifiers

PMID: 33154556
DOI: 10.1038/s41598-020-76313-w
PMCID: PMC7644694

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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