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Article

Keratin intermediate filaments in the colon: guardians of epithelial homeostasis

2 Nov 2020

Abstract excerpt

Keratin intermediate filament proteins are major cytoskeletal components of the mammalian simple layered columnar epithelium in the gastrointestinal tract. Human colon crypt epithelial cells express keratins 18, 19 and 20 as the major type I keratins, and keratin 8 as the type II keratin. Keratin expression patterns vary between species, and mouse colonocytes express keratin 7 as a second type II keratin. Colonic...

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PMID: 33152513
DOI: 10.1016/j.biocel.2020.105878

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