Article
Short-duration treatment with the novel non-nucleoside inhibitor CDI-31244 plus sofosbuvir/velpatasvir for chronic hepatitis C: An open-label study.
Journal of medical virology - 1 Jun 2021
Chua Joel V, Ntem-Mensah Afua, Abutaleb Ameer, Husson Jennifer, Mutumbi Lydiah, Lam Ka Wing, Ghosh Alip, Romani Sara, Poonia Bhawna, Lee Sam, Luz Pascual M, Frumkin Lyn R, Kottilil Shyamsundaran
Abstract excerpt
Combination regimens of direct-acting antiviral agents (DAAs) for chronic genotype 1 hepatitis C virus (HCV) infection given for 8 or 12 weeks have high cure rates. Shortened treatment durations that maintain high cure rates may lessen treatment barriers related to affordability and drug adherence. We enrolled 12 treatment-naïve adults with chronic genotype 1 HCV infection without cirrhosis in a single-center,...
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