Article
Efficacy of an interferon- and ribavirin-free regimen of daclatasvir, asunaprevir, and BMS-791325 in treatment-naive patients with HCV genotype 1 infection.
Gastroenterology - 1 Feb 2014
Everson Gregory T, Sims Karen D, Rodriguez-Torres Maribel, Hézode Christophe, Lawitz Eric, Bourlière Marc, Loustaud-Ratti Veronique, Rustgi Vinod, Schwartz Howard, Tatum Harvey, Marcellin Patrick, Pol Stanislas, Thuluvath Paul J, Eley Timothy, Wang Xiaodong, Huang Shu-Pang, McPhee Fiona, Wind-Rotolo Megan, Chung Ellen, Pasquinelli Claudio, Grasela Dennis M, Gardiner David F
Abstract excerpt
BACKGROUND & AIMS: The combination of peginterferon and ribavirin with telaprevir or boceprevir is the standard treatment of hepatitis C virus (HCV) genotype 1 infection. However, these drugs are not well tolerated because of their side effects and suboptimal virologic responses. In a phase 2a, open-label study, we examined the safety and efficacy of an interferon-free, ribavirin-free regimen of direct-acting...
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