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Are Heat Shock Proteins an Important Link between Type 2 Diabetes and Alzheimer Disease?

2 Nov 2020

Abstract excerpt

Type 2 diabetes (T2D) and Alzheimer's disease (AD) are growing in prevalence worldwide. The development of T2D increases the risk of AD disease, while AD patients can show glucose imbalance due to an increased insulin resistance. T2D and AD share similar pathological features and underlying mechanisms, including the deposition of amyloidogenic peptides in pancreatic islets (i.e., islet amyloid polypeptide; IAPP)...

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PMID: 33147803
DOI: 10.3390/ijms21218204

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