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Article

Cytauxzoon felis cytochrome b gene mutation associated with atovaquone and azithromycin treatment.

Journal of veterinary internal medicine - 1 Nov 2020

Hartley Ashley N, Marr Henry S, Birkenheuer Adam J

Abstract excerpt

BACKGROUND: Atovaquone and azithromycin (A&A) with supportive care improve survival rates in cats with cytauxzoonosis. Resistance to atovaquone via parasite cytochrome b gene (cytb) mutations occurs in other Apicomplexan protozoans but is not described in Cytauxzoon felis. OBJECTIVE: To serially characterize the C. felis cytb sequences from a cat that remained persistently infected after A&A treatment. ANIMAL: A...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33146909
DOI: 10.1111/jvim.15935
PMCID: PMC7694809

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