Article
Rapid High-Resolution Melt Analysis of Cytauxzoon felis Cytochrome b To Aid in the Prognosis of Cytauxzoonosis.
Journal of clinical microbiology - 1 Aug 2015
Schreeg Megan E, Marr Henry S, Tarigo Jaime L, Cohn Leah A, Levy Michael G, Birkenheuer Adam J
Abstract excerpt
Cytauxzoon felis is a virulent, tick-transmitted, protozoan parasite that infects felines. Cytauxzoonosis was previously thought to be uniformly fatal in domestic cats. Treatment combining atovaquone and azithromycin (A&A) has been associated with survival rates of over 60%. Atovaquone, a ubiquinone analogue, targets C. felis cytochrome b (cytb), of which 30 unique genotypes have been identified. The C. felis...
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