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Article

HER2 Heterogeneity in Gastric Cancer: A Comparative Study, Using Two Commercial Antibodies

20 Oct 2020

Abstract excerpt

Background. Although amplification of the gene encoding human epidermal growth factor receptor 2 (HER2) is used as an indicator for response to trastuzumab, the reported response rate is low, and few patients with gastric cancer (GC) benefit from this individualized therapy. The aim of this study was to examine the expression of c-erbB-2 oncoprotein (HER2), in GC samples, using two commercial immunohistochemical...

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PMID: 33144857
DOI: 10.1155/2020/8860174

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