Article
Expression of NK cell receptor ligands in primary colorectal cancer tissue in relation to the phenotype of circulating NK- and NKT cells, and clinical outcome.
Molecular immunology - 1 Dec 2020
Krijgsman Daniëlle, Roelands Jessica, Andersen Morten N, Wieringa Cornelia H L A, Tollenaar Rob A E M, Hendrickx Wouter, Bedognetti Davide, Hokland Marianne, Kuppen Peter J K
Abstract excerpt
INTRODUCTION: Natural killer (NK) cells and natural killer T (NKT) cells are implicated in the development and progression of colorectal cancer (CRC). Tumor cells express NK cell receptor ligands that modulate their function. This study aimed to investigate the expression of such ligands in CRC in relation to the phenotype of circulating NK- and NKT cells, and clinical outcome. METHODS: Primary tumor tissues were...
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