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Sensitivity and specificity of SARS-CoV-2 S1 subunit in COVID-19 serology assays

27 Oct 2020

Abstract excerpt

Serological assays such as enzyme-linked immunosorbent assays (ELISA) using SARS-CoV-2 Spike (S) proteins are practical methods to determine the extent of COVID-19 immunity in a population upon SARS-CoV-2 vaccination 1 . However, the robustness of these assays, which depends on the sensitivity and specificity of S proteins in detecting anti-SARS-CoV-2 antibodies, is not well characterized. Here, we report that...

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PMID: 33133635
DOI: 10.1038/s41421-020-00224-3

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