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Article

Generation of induced pluripotent stem cell GZHMCi002-A from peripheral blood mononuclear cells with APOB mutation.

Stem cell research - 1 Dec 2020

Bing Song, Nengqing Liu, Yi Cheng, Dian Lu, Diyu Chen, Yingjun Xie, Lina He, Yinghong Yang, Hongmei Guan, Xiaofang Sun

Abstract excerpt

Apolipoprotein (apo) B is a large, amphipathic glycoprotein which plays an important role in human lipoprotein metabolism. The 43-kb APOB gene located on the short arm of human chromosome 2 and consisted of 29 exons, mutations in the APOB gene can give rise to either hypo- or hypercholesterolemia. We used peripheral blood mononuclear cells (PBMCs) from a volunteer carrying the APOB mutation (c.10579C>T,...

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Identifiers

PMID: 33128957
DOI: 10.1016/j.scr.2020.102054

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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