Article
Genome-wide association study of self-reported walking pace suggests beneficial effects of brisk walking on health and survival.
Communications biology - 30 Oct 2020
Timmins Iain R, Zaccardi Francesco, Nelson Christopher P, Franks Paul W, Yates Thomas, Dudbridge Frank
Abstract excerpt
Walking is a simple form of exercise, widely promoted for its health benefits. Self-reported walking pace has been associated with a range of cardiorespiratory and cancer outcomes, and is a strong predictor of mortality. Here we perform a genome-wide association study of self-reported walking pace in 450,967 European ancestry UK Biobank participants. We identify 70 independent associated loci (P < 5 × 10-8), 11...
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