Article
Developmental neurotoxicity and toxic mechanisms induced by olaquindox in zebrafish.
Journal of applied toxicology : JAT - 1 Apr 2021
Guo Sheng-Ya, Zhang Yong, Zhu Xiao-Yu, Zhou Jia-Li, Li Jiao, Li Chun-Qi, Wu Li-Ren
Abstract excerpt
Olaquindox (OLA) has been widely used as an animal feed additive in China for decades; however, its toxicity and toxic mechanisms have not been well investigated. In this study, the developmental neurotoxicity and toxic mechanisms of OLA were evaluated in zebrafish. Zebrafish embryos were exposed to different concentrations of OLA (25-1,000 mg/L) from 6 to 120 hours post fertilization (hpf). OLA exposure resulted...
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