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Protective effects of pravastatin on the embryonic cardiovascular system during hypoxic development

23 Oct 2020

Abstract excerpt

Abstract The use of statins in complicated pregnancy is being considered, as they protect endothelial function in the mother and placenta. However, whether statins affect cardiovascular function in the fetus is completely unknown. Here, we have determined the effects of pravastatin and underlying mechanisms on the cardiovascular system of the hypoxic chicken embryo, a model system that permits the direct effects...

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PMID: 33094855
DOI: 10.1096/fj.202001743r

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