Article
Genetic and environmental causes of variation in epigenetic aging across the lifespan.
Clinical epigenetics - 22 Oct 2020
Li Shuai, Nguyen Tuong L, Wong Ee Ming, Dugué Pierre-Antoine, Dite Gillian S, Armstrong Nicola J, Craig Jeffrey M, Mather Karen A, Sachdev Perminder S, Saffery Richard, Sung Joohon, Tan Qihua, Thalamuthu Anbupalam, Milne Roger L, Giles Graham G, Southey Melissa C, Hopper John L
Abstract excerpt
BACKGROUND: DNA methylation-based biological age (DNAm age) is an important biomarker for adult health. Studies in specific age ranges have found widely varying results about its genetic and environmental causes of variation. However, these studies are not able to provide a comprehensive view of the causes of variation over the lifespan. RESULTS: In order to investigate the genetic and environmental causes of...
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