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Article

Variants of Focal Adhesion Scaffold Genes Cause Thoracic Aortic Aneurysm.

Circulation research - 8 Jan 2021

Li Yang, Gao Shijuan, Han Yingchun, Song Li, Kong Yu, Jiao Yao, Huang Shan, Du Jie, Li Yulin

Abstract excerpt

RATIONALE: Thoracic aortic aneurysm (TAA) leads to substantial mortality worldwide. Familial and syndromic TAAs are highly correlated with genetics. However, the incidence of sporadic isolated TAA (iTAA) is much higher, and the genetic contribution is not yet clear. OBJECTIVE: Here, we examined the genetic characteristics of sporadic iTAA. METHODS AND RESULTS: We performed a genetic screen of 551 sporadic iTAA...

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Share to Aorta, Thoracic
Share to Aortic Aneurysm, Thoracic
Share to Aortic Dissection

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cytoskeletal Proteins

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Share to Muscle, Smooth, Vascular

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Source

Identifiers

PMID: 33092471
DOI: 10.1161/CIRCRESAHA.120.317361

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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