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Decreased Histone Acetylation Levels at Th1 and Regulatory Loci after Induction of Food Allergy

19 Oct 2020

Abstract excerpt

Immunoglobulin E (IgE)-mediated allergy against cow’s milk protein fractions such as whey is one of the most common food-related allergic disorders of early childhood. Histone acetylation is an important epigenetic mechanism, shown to be involved in the pathogenesis of allergies. However, its role in food allergy remains unknown. IgE-mediated cow’s milk allergy was successfully induced in a mouse model, as...

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PMID: 33086571
DOI: 10.3390/nu12103193

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