Article
Variants in the RARRES2 gene are associated with serum chemerin and increase the risk of diabetic kidney disease in type 2 diabetes.
International journal of biological macromolecules - 15 Dec 2020
Zhao Ke, Ding Wenyu, Zhang Yong, Ma Kaihui, Wang Dong, Hu Chunhua, Liu Junjun, Zhang Xiandang
Abstract excerpt
Genetic susceptibility plays an important role in the pathogenesis of diabetic kidney disease (DKD). Recent studies have suggested that chemerin (encoded by the RARRES2 gene) is a risk factor for the development of DKD. We investigate the relationship between RARRES2 single nucleotide polymorphisms (SNPs) and DKD and their correlation with serum chemerin levels in Chinese individuals with type 2 diabetes (T2D). A...
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