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Article

Influence of NOS3 rs2070744 genotypes on hepatocellular carcinoma patients treated with lenvatinib.

Scientific reports - 13 Oct 2020

Azuma Shintaro, Uojima Haruki, Chuma Makoto, Shao Xue, Hidaka Hisashi, Nakazawa Takahide, Kondo Masaaki, Numata Kazushi, Iwabuchi Shogo, Kako Makoto, Maeda Shin, Koizumi Wasaburo, Atsuda Koichiro

Abstract excerpt

We investigated whether or not nitric oxide synthase 3 (NOS3) rs2070744 genotypes can affect the response for lenvatinib treatment in patients with hepatocellular carcinoma (HCC). We evaluated the relation of the NOS3 rs2070744 genotypes to the tumor response, progression-free survival (PFS), and overall survival (OS) as the response for lenvatinib. We also examined the association between fibroblast growth...

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Source

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Identifiers

PMID: 33051476
DOI: 10.1038/s41598-020-73930-3
PMCID: PMC7553969

Genes

NOS3
FGFR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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