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Article

Impact of Aurora Kinase A Polymorphism and Epithelial Growth Factor Receptor Mutations on the Clinicopathological Characteristics of Lung Adenocarcinoma.

International journal of environmental research and public health - 8 Oct 2020

Yang Po-Jen, Hsieh Ming-Ju, Lee Chun-I, Yen Chi-Hua, Wang Hsiang-Ling, Chiang Whei-Ling, Liu Tu-Chen, Tsao Thomas Chang-Yao, Lee Chia-Yi, Yang Shun-Fa

Abstract excerpt

Lung adenocarcinoma (LADC) is the most common subtype of lung cancer worldwide and the epidermal growth factor receptor (EGFR) has a great influence on its clinical course, mainly due to the influence of different phenotypes. The Aurora kinase A (AURKA) would influence the progression of several solid malignancies. However, whether the interaction between EGFR phenotypes and AURKA would influence the clinical...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33050100
DOI: 10.3390/ijerph17197350
PMCID: PMC7579084

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