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Anti‐VEGF DNA‐based aptamers in cancer therapeutics and diagnostics

10 Oct 2020

Abstract excerpt

The vascular endothelial growth factor (VEGF) family and its receptors play fundamental roles not only in physiological but also in pathological angiogenesis, characteristic of cancer progression. Aiming at finding putative treatments for several malignancies, various small molecules, antibodies, or protein-based drugs have been evaluated in vitro and in vivo as VEGF inhibitors, providing efficient agents...

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PMID: 33038031
DOI: 10.1002/med.21737

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