Article
Genetic polymorphism of liver X receptor gene in vitiligo: Does it have an association?
Journal of cosmetic dermatology - 1 Jun 2021
Shehata Wafaa A, Maraee Alaa, Mehesin Marwa, Tayel Nermin, Azmy Rania
Abstract excerpt
BACKGROUND: Vitiligo is an acquired depigmentation of the skin and the mucous membranes, exhibited as white macules and patches due to selective loss of melanocytes. Etiological theories of vitiligo include genetic, immunological, neurohormonal, cytotoxic, biochemical, oxidative stress, and newer theories of melanocytorrhagy and diminished melanocytes survival. It has been revealed that liver X receptor alpha...
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