Article
A fluoride-responsive genetic circuit enables in vivo biofluorination in engineered Pseudomonas putida.
Nature communications - 7 Oct 2020
Calero Patricia, Volke Daniel C, Lowe Phillip T, Gotfredsen Charlotte H, O'Hagan David, Nikel Pablo I
Abstract excerpt
Fluorine is a key element in the synthesis of molecules broadly used in medicine, agriculture and materials. Addition of fluorine to organic structures represents a unique strategy for tuning molecular properties, yet this atom is rarely found in Nature and approaches to integrate fluorometabolites into the biochemistry of living cells are scarce. In this work, synthetic gene circuits for organofluorine...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.