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Article

ICOSL + plasmacytoid dendritic cells as inducer of graft-versus-host disease, responsive to a dual ICOS/CD28 antagonist

7 Oct 2020

Abstract excerpt

-pDCs as an aGVHD biomarker and suggest that coinhibition of the ICOSL/ICOS and B7/CD28 axes with one biologic drug may represent a therapeutic opportunity to prevent or treat aGVHD.

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Identifiers

PMID: 33028709
DOI: 10.1126/scitranslmed.aay4799

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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