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Article

Long non-coding RNA CCAT1 promotes non-small cell lung cancer progression by regulating the miR-216a-5p/RAP2B axis.

Experimental biology and medicine (Maywood, N.J.) - 1 Jan 2021

Pang Lingling, Zhang Qianqian, Wu Yanmin, Yang Qingru, Zhang Jinghao, Liu Yuanyuan, Li Ruoran

Abstract excerpt

The long non-coding RNA colon cancer-associated transcript 1 (CCAT1) has been investigated to involve in the progression of non-small cell lung cancer (NSCLC). Thus, this study aims to explore the detailed molecular mechanisms of CCAT1 in NSCLC. The expression of CCAT1, miR-216a-5p, RAP2B, Bax, Bcl-2, and cleaved caspase 3 was detected by qRT-PCR or Western blot. Cell proliferation, apoptosis, migration, and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33023331
DOI: 10.1177/1535370220961013
PMCID: PMC7871119

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