Article
Molecular diagnosis, genetic diversity and drug sensitivity patterns of Mycobacterium tuberculosis strains isolated from tuberculous meningitis patients at a tertiary care hospital in South India.
PloS one - 1 Jan 2020
Krishnakumariamma Krishnapriya, Ellappan Kalaiarasan, Muthuraj Muthaiah, Tamilarasu Kadhiravan, Kumar Saka Vinod, Joseph Noyal Mariya
Abstract excerpt
Tuberculous meningitis (TBM) is the most severe form of Mycobacterium tuberculosis (Mtb) infection in humans and is a public health concern worldwide. We evaluated the performance of GeneXpert MTB/RIF (GeneXpert) for the diagnosis of TBM. In addition, genetic diversity and drug susceptibility profiling of Mtb strains isolated from TBM patients were also investigated. A total of 293 TBM suspected cerebrospinal...
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