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Article

Pyroptosis Plays a Role in Osteoarthritis

1 Jan 2020

Abstract excerpt

Recent studies have revealed novel forms of cell death beyond the canonical types of cellular apoptosis and necrosis, and these novel forms of cell death are induced by extreme microenvironmental factors. Pyroptosis, a type of regulated cell death, occurs when pattern recognition receptors (PRRs) induce the activation of cysteine-aspartic protease 1 (caspase-1) or caspase-11, which can trigger the release of the...

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PMID: 33014529
DOI: 10.14336/ad.2019.1127

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