Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

AIP variant causing familial prolactinoma.

Pituitary - 1 Feb 2021

Carty David M, Harte Rachael, Drummond Russell S, Ward Rebecca, Magid Kesson, Collier David, Owens Martina, Korbonits Márta

Abstract excerpt

Pathogenic variants in the aryl hydrocarbon receptor-interacting protein (AIP) gene are increasingly recognised as a cause of familial isolated pituitary adenoma. AIP-associated tumours are most commonly growth hormone (GH) producing. In our cohort of 175 AIP mutation positive patients representing 93 kindreds, 139 (79%) have GH excess, 19 have prolactinoma (17 familial and 2 sporadic cases) and out of the 17...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenoma
Share to Genetic Testing
Share to Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Pedigree

Share to Pituitary Neoplasms

Source

Open in PubMed Open full text

Identifiers

PMID: 33010004
DOI: 10.1007/s11102-020-01085-5
PMCID: PMC7864850

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

AIP variant causing familial prolactinoma.PMID 33010004Read ↗

Variable pathological and clinical features of a large Brazilian family harboring a mutation in the aryl hydrocarbon receptor-interacting protein geneSemantic proximity Read ↗

Low rate of germline AIP mutations in patients with apparently sporadic pituitary adenomas before the age of 40: a single-centre adult cohortSemantic proximity Read ↗

Should aip gene screening be recommended in family members of FIPA patients with R16H variant?Semantic proximity Read ↗

Molecular genetics of the aip gene in familial pituitary tumorigenesis.Semantic proximity Read ↗

Familial pituitary adenomas – who should be tested for AIP mutations?Semantic proximity Read ↗

Germline AIP mutations in apparently sporadic pituitary adenomas: prevalence in a prospective single-center cohort of 443 patients.Semantic proximity Read ↗

Aryl hydrocarbon receptor-interacting protein gene mutations in familial isolated pituitary adenomas: analysis in 73 families.Semantic proximity Read ↗

Familial isolated pituitary adenomas experience at a single center: clinical importance of AIP mutation screening.Semantic proximity Read ↗

Familial isolated pituitary adenomas (FIPA) and the pituitary adenoma predisposition due to mutations in the aryl hydrocarbon receptor interacting protein (AIP) gene.Semantic proximity Read ↗

Familial acromegaly due to aryl hydrocarbon receptor-interacting protein (AIP) gene mutation in a Turkish cohort.Semantic proximity Read ↗

Aggressive pituitary adenomas occurring in young patients in a large Polynesian kindred with a germline R271W mutation in the AIP gene.Semantic proximity Read ↗

[AIP mutations in familial and sporadic pituitary adenomas: local experience and review of the literature].Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.