Article
The c.*52 A/G and c.*773 A/G Genetic Variants in the UTR'3 of the LDLR Gene Are Associated with the Risk of Acute Coronary Syndrome and Lower Plasma HDL-Cholesterol Concentration.
Biomolecules - 29 Sept 2020
Vargas-Alarcon Gilberto, Perez-Mendez Oscar, Ramirez-Bello Julian, Posadas-Sanchez Rosalinda, Gonzalez-Pacheco Hector, Escobedo Galileo, Nieto-Lima Betzabe, Carreon-Torres Elizabeth, Fragoso Jose Manuel
Abstract excerpt
Dyslipidemia has a substantial role in the development of acute coronary syndrome (ACS). Low-density lipoprotein receptor (LDLR) plays a critical role in plasma lipoprotein hemostasis, which is involved in the formation of atherosclerotic plaque. This study aimed to evaluate whether LDLR gene polymorphisms are significantly associated with ACS and the plasma lipids profile. Three LDLR gene polymorphisms located...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.