Article
Nephronophthisis gene products display RNA-binding properties and are recruited to stress granules.
Scientific reports - 29 Sept 2020
Estrada Mallarino Luisa, Engel Christina, Ilık İbrahim Avşar, Maticzka Daniel, Heyl Florian, Müller Barbara, Yakulov Toma A, Dengjel Jörn, Backofen Rolf, Akhtar Asifa, Walz Gerd
Abstract excerpt
Mutations of cilia-associated molecules cause multiple developmental defects that are collectively termed ciliopathies. However, several ciliary proteins, involved in gating access to the cilium, also assume localizations at other cellular sites including the nucleus, where they participate in DNA damage responses to maintain tissue integrity. Molecular insight into how these molecules execute such diverse...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.