Article
Mendelian randomization study indicates lack of causal relationship between physical activity and lung cancer.
Journal of cancer research and clinical oncology - 1 Jan 2021
Xian Wei, Shen Jiayi, Zhou Huaqiang, Liu Jiaqing, Zhang Yaxiong, Zhang Zhonghan, Zhou Ting, Hong Shaodong, Yang Yunpeng, Fang Wenfeng, Zhao Hongyun, Huang Yan, Zhang Li
Abstract excerpt
BACKGROUND: Previous researches have indicated physical activity (PA) may be associated with lower risk of lung cancer. However, causal relationship between PA and risk of lung cancer is not clear. We aimed to inspect the causal effect of PA on lung cancer. METHODS: We analyzed summary data of accelerator-measured PA and lung cancer from the genome-wide association study (GWAS) using two-sample Mendelian...
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