Article
Artificial intelligence to detect MYC translocation in slides of diffuse large B-cell lymphoma.
Virchows Archiv : an international journal of pathology - 1 Sept 2021
Swiderska-Chadaj Zaneta, Hebeda Konnie M, van den Brand Michiel, Litjens Geert
Abstract excerpt
In patients with suspected lymphoma, the tissue biopsy provides lymphoma confirmation, classification, and prognostic factors, including genetic changes. We developed a deep learning algorithm to detect MYC rearrangement in scanned histological slides of diffuse large B-cell lymphoma. The H&E-stained slides of 287 cases from 11 hospitals were used for training and evaluation. The overall sensitivity to detect MYC...
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