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Article

Characterization of the adipogenic protein E4orf1 from adenovirus 36 through an in silico approach.

Journal of molecular modeling - 25 Sept 2020

Gutiérrez Alvaro, Ferreira Glaucio Monteiro, Machuca Juan, Venthur Herbert, Feres Fausto, Hirata Mario Hirouyki, Hirata Rosario Dominguez Crespo, Cerda Alvaro

Abstract excerpt

Adenovirus 36 (Ad-36) is related to human obesity due to its adipogenic activity mediated by the early 4 open reading frame 1 (E4orf1) protein. Mechanisms underlying the adipogenic effect of E4orf1 are not completely understood; however, the proliferation and differentiation of fat cells are increased through the activation of the phosphatidyl inositol 3 kinase pathway by binding proteins containing PDZ domain....

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PMID: 32978703
DOI: 10.1007/s00894-020-04531-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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