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Lions, tigers and kittens too: ACE2 and susceptibility to COVID-19

1 Jan 2020

Abstract excerpt

Abstract SARS-CoV-2 (Severe Acute Respiratory Syndrome coronavirus 2) has been reported to infect domesticated animals in a species-specific manner, where cats were susceptible but not dogs. Using the recently published crystal structure of the SARS-CoV-2 spike protein complexed with the human host cell receptor angiotensin converting enzyme 2 (ACE2), we characterized the structure and evolution of ACE2 in...

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PMID: 32974030
DOI: 10.1093/emph/eoaa021

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