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Article

The clinicopathological and molecular features of sinusoidal large B-cell lymphoma.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 May 2021

Xu Junpeng, Li Peifeng, Chai Jia, Yu Kangjie, Xu Tianqi, Zhao Danhui, Liu Yixiong, Wang Yingmei, Wang Kaijing, Ma Jing, Fan Linni, Yan Qingguo, Guo Shuangping, Xiao Hualiang, Ao Qilin, Wang Zhaoming, Liu Weiping, Zhao Sha, Yin Weihua, Huang Yuhua, Li Yaqin, He Miaoxia, Liang Rong, Li Mingyang, Wang Zhe

Abstract excerpt

We report 17 cases of sinusoidal large B-cell lymphoma (SLBCL). Clinical, morphologic, immunophenotypic, and molecular features were detected and analyzed. All cases showed an obvious sinusoidal growth pattern, usually associated with residual atrophic lymphoid tissue. All tumors contained large pleomorphic lymphoid cells and one or more prominent nucleoli, with abundant amphophilic cytoplasms; 15/17 cases showed...

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Identifiers

PMID: 32973328
DOI: 10.1038/s41379-020-00685-7

Genes

BCL2
MYC
TP53
BCL6
CREBBP
KMT2D
MYD88
PIM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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