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Spiral Artery Remodeling and Trophoblast Invasion in Preeclampsia and Fetal Growth Restriction

24 Sept 2013

Abstract excerpt

Failure to transform uteroplacental spiral arteries is thought to underpin disorders of pregnancy, including preeclampsia and fetal growth restriction (FGR). In this study, spiral artery remodeling and extravillous-cytotrophoblast were examined in placental bed biopsies from normal pregnancy (n = 25), preeclampsia (n = 22), and severe FGR (n = 10) and then compared with clinical parameters. Biopsies were...

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PMID: 24060885
DOI: 10.1161/hypertensionaha.113.01892

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