Article
MapGL: inferring evolutionary gain and loss of short genomic sequence features by phylogenetic maximum parsimony.
BMC bioinformatics - 22 Sept 2020
Diehl Adam G, Boyle Alan P
Abstract excerpt
BACKGROUND: Comparative genomics studies are growing in number partly because of their unique ability to provide insight into shared and divergent biology between species. Of particular interest is the use of phylogenetic methods to infer the evolutionary history of cis-regulatory sequence features, which contribute strongly to phenotypic divergence and are frequently gained and lost in eutherian genomes....
Topics
- Animals
- Evolution, Molecular
- Genome
- Genomics
- Humans
- Mammals
- Phenotype
- Phylogeny
- Regulatory Sequences, Nucleic Acid
- Software