Article
Ramucirumab or placebo plus erlotinib in EGFR-mutated, metastatic non-small-cell lung cancer: East Asian subset of RELAY.
Cancer science - 1 Dec 2020
Nishio Makoto, Seto Takashi, Reck Martin, Garon Edward B, Chiu Chao-Hua, Yoh Kiyotaka, Imamura Fumio, Park Keunchil, Shih Jin-Yuan, Visseren-Grul Carla, Frimodt-Moller Bente, Zimmermann Annamaria, Homma Gosuke, Enatsu Sotaro, Nakagawa Kazuhiko
Abstract excerpt
In the global phase III RELAY study, ramucirumab plus erlotinib (RAM + ERL) demonstrated superior progression-free survival (PFS) to placebo plus erlotinib (PL + ERL) in untreated patients with epidermal growth factor receptor (EGFR) mutation-positive metastatic non-small-cell lung cancer (NSCLC) (hazard ratio (HR) [95% CI]: 0.59 [0.46-0.76]). This prespecified analysis assessed RAM + ERL efficacy and safety in...
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