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RELAY, Ramucirumab Plus Erlotinib (RAM+ERL) in Untreated Metastatic EGFR-Mutant NSCLC (EGFR+ NSCLC): Association Between TP53 Status and Clinical Outcome.

Clinical lung cancer - 1 Jul 2023

Nishio Makoto, Paz-Ares Luis, Reck Martin, Nakagawa Kazuhiko, Garon Edward B, Popat Sanjay, Ceccarelli Matteo, Graham Hillary T, Visseren-Grul Carla, Novello Silvia

Abstract excerpt

BACKGROUND: Ramucirumab plus erlotinib (RAM+ERL) demonstrated superior progression-free survival (PFS) in RELAY, a randomised Phase III trial in patients with untreated, metastatic, EGFR-mutated, non-small-cell lung cancer (EGFR+ NSCLC). Here, we present the relationship between TP53 status and outcomes in RELAY. MATERIALS AND METHODS: Patients received oral ERL plus intravenous RAM (10 mg/kg IV) or placebo...

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PMID: 37076395
DOI: 10.1016/j.cllc.2023.02.010

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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