Article
Telomere length and type 2 diabetes: Mendelian randomization study and polygenic risk score analysis.
Yi chuan = Hereditas - 20 Sept 2020
Cao Lan, Li Zhi Qiang, Shi Yong Yong, Liu Yun
Abstract excerpt
Recent epidemiological studies suggest an association between shorter telomere length and higher risk for type 2 diabetes (T2D). However, results from observational studies are susceptible to confounding and reverse causation, and it is not clear whether there is a causal association between telomere length and T2D. Using Mendelian randomization (MR) and polygenic risk score (PRS) approaches, we had evaluated the...
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