Article
Mutation profiling in eight cases of vagal paragangliomas.
BMC medical genomics - 18 Sept 2020
Kudryavtseva Anna V, Kalinin Dmitry V, Pavlov Vladislav S, Savvateeva Maria V, Fedorova Maria S, Pudova Elena A, Kobelyatskaya Anastasiya A, Golovyuk Alexander L, Guvatova Zulfiya G, Razmakhaev George S, Demidova Tatiana B, Simanovsky Sergey A, Slavnova Elena N, Poloznikov Andrey А, Polyakov Andrey P, Melnikova Nataliya V, Dmitriev Alexey A, Krasnov George S, Snezhkina Anastasiya V
Abstract excerpt
BACKGROUND: Vagal paragangliomas (VPGLs) belong to a group of rare head and neck neuroendocrine tumors. VPGLs arise from the vagus nerve and are less common than carotid paragangliomas. Both diagnostics and therapy of the tumors raise significant challenges. Besides, the genetic and molecular mechanisms behind VPGL pathogenesis are poorly understood. METHODS: The collection of VPGLs obtained from 8 patients of...
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