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Article

PLCγ1‑dependent invasion and migration of cells expressing NSCLC‑associated EGFR mutants.

International journal of oncology - 1 Oct 2020

Mittal Sonam, Kamath Arpana, Joseph Ann M, Rajala Maitreyi S

Abstract excerpt

The increased tyrosine kinase activity of non‑small cell lung cancer (NSCLC)‑associated epidermal growth factor receptor (EGFR) mutants results in deregulated pathways that contribute to malignant cell survival, tumor progression and metastasis. Previous studies investigating lung cancer‑associated EGFR have focused on the prognostic implications of receptor kinase mutations in patients with NSCLC; however, the...

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PMID: 32945365
DOI: 10.3892/ijo.2020.5112

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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