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Article

A novel RUNX1 mutation with ANKRD26 dysregulation is related to thrombocytopenia in a sporadic form of myelodysplastic syndrome.

Aging clinical and experimental research - 1 Jul 2021

Ferrari Silvia, Regazzo Daniela, Omenetto Elisabetta, Scaroni Carla, Semenzato Gianpietro, Fabris Fabrizio, Vianello Fabrizio

Abstract excerpt

Aging is associated with a higher risk of developing malignant diseases, including myelodysplastic syndromes, clonal disorders characterised by chronic cytopenias (anaemia, neutropenia and thrombocytopenia) and abnormal cellular maturation. Myelodysplastic syndromes arising in older subjects are influenced by combinations of acquired somatic genetic lesions driving evolution from clonal haematopoiesis to...

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PMID: 32944898
DOI: 10.1007/s40520-020-01709-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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