Familial myelodysplastic syndromes: a review of the literature

Abstract excerpt

Familial cases of myelodysplastic syndromes are rare, but are immensely valuable for the investigation of the molecular pathogenesis of myelodysplasia in general. The best-characterized familial myelodysplastic syndrome is that of familial platelet disorder with propensity to myeloid malignancy, caused by heterozygous germline RUNX1 mutations. Recently, there has been an increase in the number of reported cases,...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Acute Myeloid Leukemia Research
• Share to Neutrophil, Myeloperoxidase and Oxidative Mechanisms
• Share to Telomeres, Telomerase, and Senescence