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Article

Prevalence and natural history of variants in the ANKRD26 gene: a short review and update of reported cases.

Platelets - 17 Nov 2022

Vyas Hrushikesh, Alcheikh Ahmad, Lowe Gillian, Stevenson William S, Morgan Neil V, Rabbolini David J

Abstract excerpt

ANKRD26 is a highly conserved gene located on chromosome 10p12.1 which has shown to play a role in normal megakaryocyte differentiation. ANKRD26-related thrombocytopenia, or thrombocytopenia 2, is an inherited thrombocytopenia with mild bleeding diathesis resulting from point mutations the 5'UTR of the ANKRD26 gene. Point mutations in the 5'UTR region have been shown to prevent transcription factor-mediated...

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Identifiers

PMID: 35587581
DOI: 10.1080/09537104.2022.2071853
PMCID: PMC9555274

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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