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Article

Emergence of genotype C1 Enterovirus A71 and its link with antigenic variation of virus in Taiwan.

PLoS pathogens - 1 Sept 2020

Huang Kuan-Ying A, Huang Peng-Nien, Huang Yhu-Chering, Yang Shu-Li, Tsao Kuo-Chien, Chiu Cheng-Hsun, Shih Shin-Ru, Lin Tzou-Yien

Abstract excerpt

An outbreak of the hand-foot-mouth disease with severe neurological cases, mainly caused by the genotype C1 enterovirus A71 (EV-A71), occurred in Taiwan between 2018 and early 2019. In the recent decade, the most dominant EV-A71 genotypes in Taiwan were B5 and C4 but changed to C1 in 2018. Antibody-mediated immunity plays a key role in limiting the EV-A71 illness in humans. However, the level of neutralizing...

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Identifiers

PMID: 32936838
DOI: 10.1371/journal.ppat.1008857
PMCID: PMC7521691

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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