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Article

Emergence of a non vaccine-cognate enterovirus A71 genotype C1 in mainland China.

The Journal of infection - 1 Mar 2021

Zeng Hanri, Yi Lina, Chen Xiaoli, Zhou Huiqiong, Zheng Huanying, Lu Jing, Yang Fen, Li Caixia, Fang Ling, Zhang Xin, Jing Xu, Wu Jie, Li Hui

Abstract excerpt

BACKGROUND: EV-A71 is a common causative agent of hand foot and mouth disease. In mainland China, EV-A71 subgenotype C4 has been the sole circulating genotype since 2008, and was used in the production of multiple licensed vaccines. Here, we report the first detection EV-A71 C1 strains in China. METHODS: Full genomic sequence were obtained. The origin of the EV-A71 C1 strains were tracked down by Bayesian...

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PMID: 33373653
DOI: 10.1016/j.jinf.2020.12.020

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