Article
Association of cytokines levels with epidermal growth factor receptor mutation in lung cancer patients.
Journal of cancer research and therapeutics - 1 Jan 2000
Gaur Priyanka, Bhattacharya Sandeep, Kant Surya, Kushwaha R A S, Singh Gaurav, Pandey Sarika
Abstract excerpt
BACKGROUND: Lung cancer is one of the most frequent types of cancer and the leading cause of cancer-related deaths. Epidermal growth factor receptor (EGFR) is a receptor tyrosine kinase (TK) being highly expressed in lung cancers. Activation of EGFR through oncogenic mutations leads to upregulation of gene expression that may heighten the inflammatory response in certain situations. EGFR acts as a key regulator...
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